Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901768 | 0.76 | TDP1 (0.44) | MAPTTDP1ATM | |
| SCHEMBL8902192 | 0.76 | TDP1 (0.44) | MAPTTDP1ATM | |
| SCHEMBL8901784 | 0.71 | TDP1 (0.46) | MAPTHTTTDP1ATM | |
| SCHEMBL8903959 | 0.70 | CYP1A2 (0.35) | MAPTCACNA1GHTTDRD4TERT | |
| SCHEMBL8901821 | 0.66 | L3MBTL1 (0.39) | MAPTHTT | |
| SCHEMBL9755756 | 0.66 | SMN1; SMN2 (0.40) | MAPTHTT | |
| SCHEMBL8902603 | 0.64 | AKT1 (0.36) | MAPTTDP1 | |
| SCHEMBL27861034 | 0.58 | LOXL2 (0.48) | — | |
| SCHEMBL8543345 | 0.58 | TSHR (0.50) | MAPT | |
| Bicarbonate SCHEMBL30096531 | 0.57 | ALDH1A1 (0.64) | MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |