Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010707 | 0.77 | ABCB1 (0.77) | ABCB1ABCC1MEN1KMT2AMAPK1 | |
| SCHEMBL12474528 | 0.74 | TUBB4A (0.52) | ABCB1ABCC1MEN1KMT2AHTT | |
| SCHEMBL2234880 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AHTTALDH1A1TUBB4A | |
| SCHEMBL375443 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2AHTTALDH1A1TUBB4A | |
| SCHEMBL12474512 | 0.71 | TUBB4A (0.49) | ABCB1ABCC1MEN1KMT2AHTT | |
| SCHEMBL4824442 | 0.70 | TUBB4A (0.60) | ABCB1ABCC1MEN1KMT2AMAPK1 | |
| SCHEMBL7368386 | 0.70 | TTR (0.58) | ABCB1ABCC1MEN1KMT2ADBH | |
| SCHEMBL224904 | 0.70 | ALDH1A1 (0.56) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL4818707 | 0.69 | TUBB4A (0.62) | KMT2AALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL1447399 | 0.69 | TPMT (0.74) | ABCB1ABCC1MEN1KMT2ADBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |