Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903726 | 0.86 | MAPK1 (0.35) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL8971528 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HPGD | |
| SCHEMBL3027865 | 0.79 | ALDH1A1 (0.50) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL829468 | 0.78 | TP53 (0.36) | TP53L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL4361446 | 0.78 | TP53 (0.36) | TP53L3MBTL1ADORA1ADORA3ADORA2A | |
| Potassium Ion SCHEMBL4148709 | 0.76 | TP53 (0.35) | TP53L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL7885590 | 0.76 | ALDH1A1 (0.44) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL2778487 | 0.72 | TP53 (0.44) | TP53L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL11051317 | 0.72 | TP53 (0.40) | TP53L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL4607159 | 0.71 | LMNA (0.41) | TP53L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604251-A | Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-18 | — | — | US | disclosed |