SCHEMBL829468

SCHEMBL829468

CCc1nc(C)c(C(=S)S)[nH]1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ADORA1 P30542 4/20 0.35
ADORA3 P0DMS8 3/20 0.35
ADORA2A P29274 2/20 0.35
DDAH1 O94760 1/20 0.32
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4361446 0.81 TP53 (0.36) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL828425 0.80 GPR84 (0.43)
Potassium Ion SCHEMBL4148709 0.79 TP53 (0.35) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL8901944 0.78 TP53 (0.34) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL828058 0.75 ALDH1A1 (0.33) L3MBTL1ADORA3
SCHEMBL2778487 0.74 TP53 (0.44) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL11051317 0.74 TP53 (0.40) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL3027865 0.70 ALDH1A1 (0.50) L3MBTL1HTT
SCHEMBL4607159 0.70 LMNA (0.41) TP53L3MBTL1HTT
SCHEMBL31228920 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069443-B1 IMIDAZOLES, THEIR PRODUCTION AND THEIR USE IN PREVENTING CORROSION OF SILVER SHIKOKU CHEMICALS CORPORATION (JP) 1984-11-07 EP claimed
US-4394511-A Imidazole 4(5)-dithiocarboxylic acids or salts SHIKOKU CHEMICALS CORPORATION (JP) 1983-07-19 US claimed
EP-0069443-A1 Imidazoles, their production and their use in preventing corrosion of silver SHIKOKU CHEMICALS CORPORATION (JP) 1983-01-12 EP claimed
CN-108276567-B Application of ionic liquid as catalyst in preparation of liquid crystal polyester and preparation method of liquid crystal polyester 金发科技股份有限公司 2020-07-14 CN disclosed
EP-1728898-B1 Electrolytes for the deposition of gold alloys ROHM & HAAS ELECT MAT (US) 2017-02-22 EP disclosed
US-8202448-B2 Liquid-crystalline polyester resin composition and connector using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-19 US disclosed
US-8142637-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-27 US disclosed
US-20100163796-A1 LIQUID-CRYSTALLINE POLYESTER RESIN COMPOSITION AND CONNECTOR USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 US disclosed
US-20090104463-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC 2009-04-23 US disclosed
US-7465385-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2008-12-16 US disclosed
US-20070122637-A1 Aromatic liquid-crystalline polyester film and metal laminated article SUMITOMO CHEMICAL COMPANY, LIMITED 2007-05-31 US disclosed
US-20030168634-A1 Liquid crystalline polyester resin composition for a connector SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-11 US disclosed
US-6512079-B2 Acylating aromatic diol and/or aromatic hydroxycarboxylic acid with fatty anhydride, then transesterifying, in presence of imidazole based compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-28 US disclosed
US-20020055607-A1 Liquid crystalline polyester and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-09 US disclosed
EP-1184401-A1 Liquid crystalline polyester and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-06 EP disclosed
EP-0069443-B1 IMIDAZOLES, THEIR PRODUCTION AND THEIR USE IN PREVENTING CORROSION OF SILVER SHIKOKU CHEMICALS CORPORATION (JP) 1984-11-07 EP disclosed
US-4469622-A Method for preventing rusting in silver by using novel imidazole-4(5)-dithiocarboxylic acids in organic solvent SHIKOKU CHEMICALS CORPORATION (JP) 1984-09-04 US disclosed
US-4431818-A Process of preparing imidazole 4(5) dithiocarboxylic acid SHIKOKU CHEMICAL CORPORATION (JP) 1984-02-14 US disclosed
US-4394511-A Imidazole 4(5)-dithiocarboxylic acids or salts SHIKOKU CHEMICALS CORPORATION (JP) 1983-07-19 US disclosed
EP-0069443-A1 Imidazoles, their production and their use in preventing corrosion of silver SHIKOKU CHEMICALS CORPORATION (JP) 1983-01-12 EP disclosed