Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 12/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7459792 | 0.89 | CHRM4 (0.44) | CHRM4CHRM5CHRM3MCHR1CCR3 | |
| SCHEMBL8313258 | 0.84 | CHRM4 (0.56) | CHRM4CHRM3HTR1ACYP2D6DRD2 | |
| Hydrochloric Acid SCHEMBL7463264 | 0.84 | LMNA (0.46) | CHRM4CHRM5CHRM3MCHR1CHRM2 | |
| SCHEMBL7463216 | 0.82 | MCHR1 (0.60) | CHRM4CHRM5CHRM3MCHR1CHRM2 | |
| Hydrochloric Acid SCHEMBL7469999 | 0.81 | MCHR1 (0.59) | CHRM4CHRM5CHRM3MCHR1CHRM2 | |
| SCHEMBL7470954 | 0.80 | CCR3 (0.61) | CCR3CCR1 | |
| SCHEMBL7470176 | 0.79 | CHRM4 (0.48) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7461078 | 0.79 | CCR3 (0.60) | CCR3CCR1 | |
| SCHEMBL7464873 | 0.78 | MCHR1 (0.56) | CHRM4CHRM5CHRM3MCHR1CCR3 | |
| SCHEMBL7459803 | 0.78 | CHRM4 (0.50) | CHRM4CHRM3CCR3HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |