Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903700 | 0.80 | KMT2A (0.42) | NLRP3KMT2AALDH1A1GAA | |
| SCHEMBL9771602 | 0.75 | KMT2A (0.35) | NLRP3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL8903199 | 0.74 | NLRP3 (0.40) | NLRP3ALDH1A1GAA | |
| SCHEMBL6085223 | 0.70 | ALDH1A1 (0.40) | NLRP3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL14266385 | 0.67 | KMT2A (0.53) | NLRP3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL19121210 | 0.67 | TRPA1 (0.44) | NLRP3KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL7686136 | 0.67 | KMT2A (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL9771590 | 0.66 | ATM (0.44) | KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL19156162 | 0.66 | KMT2A (0.43) | NLRP3KMT2AALDH1A1MEN1CES2 | |
| SCHEMBL463311 | 0.66 | KCNH2 (0.42) | NLRP3KMT2AALDH1A1GAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2598540-B2 | — | — | 1997-04-09 | — | — | JP | claimed |
| CN-1039590-A | Alkoxy-1, 2, 4-triazolo [1, 5-C ] pyrimidine-2-sulfonamides, processes for their preparation and intermediates | DOW CHEMICAL CO (US) | 1990-02-14 | — | — | CN | claimed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | claimed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | claimed |
| US-4799952-A | Herbicidal imidazolo(1,2-a)pyrimidine-2-sulfonanilides | THE DOW CHEMICAL COMPANY (US) | 1989-01-24 | — | — | US | disclosed |