Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731276 | 0.87 | ESRRA (0.38) | TNFRSF1AEGFRRARARARBRARG | |
| SCHEMBL9179855 | 0.86 | RARG (0.41) | TNFRSF1ARXRARXRBRXRGRARA | |
| SCHEMBL7987373 | 0.85 | TNFRSF1A (0.37) | TNFRSF1AEGFRRXRARXRBRXRG | |
| SCHEMBL8779698 | 0.85 | EGFR (0.48) | TNFRSF1AEGFRCA12CA1CA2 | |
| SCHEMBL9162907 | 0.85 | TSHR (0.42) | TNFRSF1AEGFR | |
| SCHEMBL9623299 | 0.84 | PLAU (0.45) | TNFRSF1ARXRARXRBRXRGRARA | |
| SCHEMBL7792646 | 0.83 | TSHR (0.42) | TNFRSF1ARXRARXRBRXRGRARG | |
| SCHEMBL4783649 | 0.81 | VCAM1 (0.39) | TNFRSF1AEGFRPTGS2 | |
| SCHEMBL3637333 | 0.80 | TNFRSF1A (0.56) | TNFRSF1ARARARARBRARGEPHX2 | |
| SCHEMBL8807107 | 0.79 | ALDH1A1 (0.39) | EGFRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0675124-A2 | Purine derivatives and suppressants for inflammatory diseases | JAPAN ENERGY CORPORATION (JP) | 1995-10-04 | — | — | EP | disclosed |