Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903140 | 0.85 | TNFRSF1A (0.40) | TNFRSF1AEGFR | |
| SCHEMBL4731276 | 0.85 | ESRRA (0.38) | LMNATNFRSF1AEGFRRECQLPTPN1 | |
| SCHEMBL8779698 | 0.84 | EGFR (0.48) | TSHRLMNAALDH1A1TNFRSF1AEGFR | |
| SCHEMBL7987373 | 0.84 | TNFRSF1A (0.37) | LMNATNFRSF1AEGFRMAPK1RECQL | |
| SCHEMBL3579165 | 0.81 | TNFRSF1A (0.51) | TSHRNCOA1NCOA3BPTFHTT | |
| SCHEMBL4783649 | 0.80 | VCAM1 (0.39) | LMNAALDH1A1TNFRSF1AEGFRMAPK1 | |
| SCHEMBL1728858 | 0.79 | CREBBP (0.39) | LMNAFYNSMN1; SMN2TNFRSF1AEGFR | |
| SCHEMBL8807107 | 0.78 | ALDH1A1 (0.39) | TSHRHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4728139 | 0.77 | EGFR (0.35) | LMNAALDH1A1TNFRSF1AEGFRMAPK1 | |
| SCHEMBL9161090 | 0.75 | DHFR (0.38) | TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441984-A | Antidiabetic agent | ELI LILLY AND COMPANY (US) | 1995-08-15 | — | — | US | disclosed |