Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.61 |
| ▸ | PGR | P06401 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.60 |
| ▸ | SHBG | P04278 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607348 | 0.90 | NR3C1 (0.79) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL10598529 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| SCHEMBL10429009 | 0.88 | NR3C1 (0.76) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL4545 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL13026141 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL23975175 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| SCHEMBL10429011 | 0.88 | NR3C1 (0.76) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL4323075 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| Fludrocortisone SCHEMBL19327146 | 0.88 | NR3C1 (1.00) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 | |
| SCHEMBL11236450 | 0.88 | NR3C1 (0.76) | NR3C1ALDH1A1MAPK1CYP2C19SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501373-B | A kind of preparation method of danabol | 湖南科瑞生物制药股份有限公司 | 2019-11-05 | — | — | CN | claimed |
| CN-107501373-A | A kind of preparation method of danabol | 湖南科瑞生物制药股份有限公司 | 2017-12-22 | — | — | CN | claimed |
| US-5667783-A | Method of treating HIV positive subjects | Alen, Constantine (US) | 1997-09-16 | — | — | US | claimed |
| US-11965199-B2 | 21-hydroxylation of steroids | SANOFI (FR) | 2024-04-23 | — | — | US | disclosed |
| US-11608514-B2 | 21-hydroxylation of steroids | EUROAPI | 2023-03-21 | — | — | US | disclosed |
| US-20220228189-A1 | 21-Hydroxylation of Steroids | EUROAPI (FR) | 2022-07-21 | — | — | US | disclosed |
| CN-114540453-A | 21-hydroxylation of steroids | 赛诺菲 | 2022-05-27 | — | — | CN | disclosed |
| EP-3957739-A1 | 21-HYDROXYLATION OF STEROIDS | SANOFI (FR) | 2022-02-23 | — | — | EP | disclosed |
| CN-108138215-B | 21-hydroxylation of steroids | 赛诺菲 | 2022-01-25 | — | — | CN | disclosed |
| EP-3212800-B1 | 21-HYDROXYLATION OF STEROIDS | SANOFI SA (FR) | 2021-09-15 | — | — | EP | disclosed |
| CN-111065409-A | STREP-TAG specific binding protein and application thereof | 弗雷德哈钦森癌症研究中心 | 2020-04-24 | — | — | CN | disclosed |
| CN-107501373-A | A kind of preparation method of danabol | 湖南科瑞生物制药股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| US-20170321241-A1 | 21-Hydroxylation of Steroids | EUROAPI FRANCE (FR) | 2017-11-09 | — | — | US | disclosed |
| EP-3212800-A1 | 21-HYDROXYLATION OF STEROIDS | SANOFI (FR) | 2017-09-06 | — | — | EP | disclosed |
| US-9638703-B2 | Quantification of glucocorticoids in fish scales as biomarkers for chronic stress | UNIVERSITEIT GENT (BE) | 2017-05-02 | — | — | US | disclosed |
| CN-106456846-A | Chitosan and polyethylene glycol copolymers and methods and devices for sealing vascular perforations using the same | 通合公司 | 2017-02-22 | — | — | CN | disclosed |
| WO-2016066738-A1 | 21-HYDROXYLATION OF STEROIDS | SANOFI (FR) | 2016-05-06 | — | — | WO | disclosed |
| EP-3015550-A1 | 21-Hydroxylation of steroids | SANOFI (FR) | 2016-05-04 | — | — | EP | disclosed |
| CN-101730538-B | Imaging and therapy of virus-associated tumors | UNIV JOHNS HOPKINS | 2015-04-29 | — | — | CN | disclosed |
| CN-101730538-A | Imaging and therapy with viral related neoplasms | UNIV JOHNS HOPKINS | 2010-06-09 | — | — | CN | disclosed |