Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TCF4 | P15884 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902595 | 0.96 | CTH (0.36) | IDO1CTHDNMT3BHSP90AA1PAX8 | |
| SCHEMBL8902603 | 0.88 | AKT1 (0.36) | IDO1CTHDNMT3BHSP90AA1PAX8 | |
| SCHEMBL8901558 | 0.85 | DNMT3B (0.44) | IDO1CTHDNMT3BHSP90AA1PAX8 | |
| SCHEMBL8902846 | 0.84 | AKT1 (0.33) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL9755764 | 0.82 | ADORA3 (0.35) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL8901769 | 0.81 | NQO1 (0.41) | IDO1CTHDNMT3BHSP90AA1PAX8 | |
| SCHEMBL8903519 | 0.79 | NR1D1 (0.33) | CTHADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL8903221 | 0.79 | NR1D1 (0.33) | CTHADORA3ADORA2AADORA1KDM4E | |
| SCHEMBL8901727 | 0.77 | KDM4E (0.34) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL9755801 | 0.77 | KDM4E (0.34) | IDO1CTHDNMT3BHSP90AA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |