Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128578 | 0.92 | REN (0.44) | CCKBRCTSSCTSBCTSKCTSL | |
| SCHEMBL7355085 | 0.87 | PTGER4 (0.55) | CTSSCTSBCTSKCTSLPTGER4 | |
| SCHEMBL8495773 | 0.87 | PTGER4 (0.55) | CTSSCTSBCTSKCTSLPTGER4 | |
| SCHEMBL5419016 | 0.87 | PTGER4 (0.55) | CTSSCTSBCTSKCTSLPTGER4 | |
| SCHEMBL14969280 | 0.87 | NPY4R (0.39) | RENNPY4R | |
| SCHEMBL9787696 | 0.86 | CTSS (0.58) | CTSSCTSBCTSKCTSLAKT1 | |
| SCHEMBL4413420 | 0.84 | PTGER4 (0.58) | CTSSCTSLPTGER4 | |
| SCHEMBL7358758 | 0.84 | PTGER4 (0.58) | CTSSCTSLPTGER4 | |
| SCHEMBL9022219 | 0.84 | PTGER4 (0.46) | PTGER4NPY4R | |
| SCHEMBL3734177 | 0.83 | MAP1LC3B (0.42) | PTGER4RENNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665366-A | APPLYING ONE OR MORE STRATUM CORNEUM TRYPSIN-LIKE ENZYME FOR DRY FLAKY SKIN CONDITIONS, DANDRUFF OR ACNE | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1997-09-09 | — | — | US | claimed |
| US-5665366-A | APPLYING ONE OR MORE STRATUM CORNEUM TRYPSIN-LIKE ENZYME FOR DRY FLAKY SKIN CONDITIONS, DANDRUFF OR ACNE | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0719133-A1 | SKIN CARE METHOD AND COMPOSITION | UNILEVER PLC (GB) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007688-A1 | SKIN CARE METHOD AND COMPOSITION | UNILEVER PLC (GB) | 1995-03-23 | — | — | WO | disclosed |