Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 6/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734177 | 0.88 | MAP1LC3B (0.42) | NPY4RRENMAP1LC3BMAP1LC3ANPY1R | |
| SCHEMBL8903646 | 0.87 | CCKBR (0.45) | NPY4RREN | |
| SCHEMBL7698946 | 0.82 | PTGER4 (0.53) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL1575643 | 0.80 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30141950 | 0.80 | CAPN1 (0.46) | NPY4RRENNPY1RNPY2RNPY5R | |
| SCHEMBL11128578 | 0.79 | REN (0.44) | NPY4RREN | |
| SCHEMBL2334528 | 0.79 | CA12 (0.45) | NPY4RMAP1LC3BMAP1LC3ANPY1RNPY2R | |
| SCHEMBL7358758 | 0.76 | PTGER4 (0.58) | — | |
| SCHEMBL4413420 | 0.76 | PTGER4 (0.58) | — | |
| SCHEMBL9003006 | 0.76 | NPY4R (0.40) | NPY4RNPY1RNPY2RNPY5RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200405767-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2020-12-31 | — | — | US | disclosed |
| EP-3563860-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | Astellas Institute for Regenerative Medicine (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-2780022-B1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | ASTELLAS INST FOR REGENERATIVE MEDICINE (US) | 2019-06-05 | — | — | EP | disclosed |
| US-20150366915-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | OCATA THERAPEUTICS, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| EP-2780022-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | Advanced Cell Technology, Inc. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013074681-A9 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | ADVANCED CELL TECHNOLOGY, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| US-20130195806-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | ADVANCED CELL TECHNOLOGY, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| WO-2013074681-A1 | PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS AND USES THEREOF | ADVANCED CELL TECHNOLOGY, INC. (US) | 2013-05-23 | — | — | WO | disclosed |