Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904310 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8712774 | 0.85 | ITGB3 (0.43) | CNR2CNR1ITGB3ITGA2BITGAV | |
| SCHEMBL8905600 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8903869 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8905965 | 0.74 | PLAU (0.40) | CNR1PLAUSIRT2ALDH1A1 | |
| SCHEMBL7392208 | 0.71 | ITGB3 (0.44) | CNR2CNR1ITGB3ITGA2BITGAV | |
| SCHEMBL7229783 | 0.71 | ITGB3 (0.54) | CNR2CNR1ITGB3ITGA2BITGAV | |
| SCHEMBL7279566 | 0.71 | ITGB3 (0.54) | CNR2CNR1ITGB3ITGA2BITGAV | |
| SCHEMBL8718269 | 0.71 | KMT2A (0.44) | PLAUALDH1A1NPSR1 | |
| SCHEMBL8713085 | 0.70 | ITGB3 (0.60) | ITGB3ITGA2BPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |