Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904325 | 1.00 | PTGS2 (0.54) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8422918 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8645474 | 0.87 | PTGS2 (0.51) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8905957 | 0.84 | MAPT (0.53) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8905953 | 0.84 | MAPT (0.53) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8927014 | 0.83 | ALDH1A1 (0.69) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8927017 | 0.83 | ALDH1A1 (0.69) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8905881 | 0.83 | APP (0.53) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL8905866 | 0.83 | APP (0.53) | PTGS2PTGS1APPMAPTNPC1 | |
| SCHEMBL10399728 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1APPMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5598005-A | Non-destructive method for determining the extent of cure of a polymerizing material and the solidification of a thermoplastic polymer based on wavelength shift of fluroescence | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE COMMERCE (US) | 1997-01-28 | — | — | US | disclosed |