Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 13/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905715 | 0.86 | RXRA (0.40) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL8904383 | 0.80 | RXRA (0.44) | GAATSHRRXRARXRBRXRG | |
| SCHEMBL8904386 | 0.80 | RXRA (0.44) | GAATSHRRXRARXRBRXRG | |
| SCHEMBL8904922 | 0.74 | PTPN11 (0.42) | RXRAHNF4ACYP3A4MEN1KMT2A | |
| SCHEMBL7207067 | 0.69 | RARB (0.63) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL7207075 | 0.69 | RARB (0.63) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL1646799 | 0.68 | ALDH1A1 (0.51) | GAAHNF4ACYP3A4MEN1KMT2A | |
| SCHEMBL8905100 | 0.66 | RXRA (0.53) | RXRARXRBRXRGHNF4ARARA | |
| SCHEMBL7213606 | 0.66 | RXRA (0.55) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7213602 | 0.66 | RXRA (0.55) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |