Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.86 |
| ▸ | PGR | P06401 | 6/20 | 0.86 |
| ▸ | AR | P10275 | 5/20 | 0.86 |
| ▸ | USP2 | O75604 | 1/20 | 0.86 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12323211 | 0.93 | NR3C1 (0.86) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL4335 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL13026159 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL10019829 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL4336 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL24015431 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL5489567 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL5188866 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL8467031 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| Halcinonide SCHEMBL7861670 | 0.92 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | NR3C1 310/4885CYP3A4 1894/4885PGR 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.