Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317001 | 0.87 | GHSR (0.48) | GHSRMMEACE2ACECPA1 | |
| SCHEMBL6324685 | 0.87 | ALDH1A1 (0.49) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL6319028 | 0.87 | ALDH1A1 (0.49) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL8904944 | 0.81 | MMP2 (0.46) | CTSKADAM17MMP2MMP9MMP8 | |
| SCHEMBL6317903 | 0.80 | GHSR (0.44) | GHSRADAM17CTSCHPGDS | |
| SCHEMBL8906561 | 0.80 | MME (0.40) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL7648964 | 0.80 | GHSR (0.58) | GHSRCTSKADAM17MMEHPGDS | |
| SCHEMBL6318779 | 0.80 | GHSR (0.72) | GHSRMMEACE2ACECPA1 | |
| SCHEMBL6318768 | 0.80 | GHSR (0.72) | GHSRMMEACE2ACECPA1 | |
| SCHEMBL6317191 | 0.80 | GHSR (0.49) | GHSRCTSKADAM17MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | claimed |