Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904886 | 0.82 | PLAU (0.49) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL8713054 | 0.80 | RAB9A (0.47) | ALDH1A1MAPTSMN1; SMN2POLBDRD2 | |
| SCHEMBL8718269 | 0.78 | KMT2A (0.44) | PLAUEPHX2F2PLGKLKB1 | |
| SCHEMBL9238331 | 0.78 | MLYCD (0.53) | CYP11B1CYP11B2ALDH1A1MAPTSIRT2 | |
| SCHEMBL8715687 | 0.77 | CETP (0.41) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL1338556 | 0.74 | CYP11B1 (0.60) | CYP11B1CYP11B2ALDH1A1MAPTSAE1 | |
| SCHEMBL8905183 | 0.74 | CNR2 (0.41) | PLAUALDH1A1SIRT2CNR1 | |
| SCHEMBL8988613 | 0.73 | RORC (0.55) | CYP11B1CYP11B2ALDH1A1MAPTSAE1 | |
| SCHEMBL7389712 | 0.73 | NCEH1 (0.41) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL3628694 | 0.71 | CYP11B1 (0.56) | CYP11B1CYP11B2ALDH1A1MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |