Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.47 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | HNF4A | P41235 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906016 | 0.97 | RXRA (0.44) | RXRARARBRARGRARARXRB | |
| SCHEMBL8904420 | 0.83 | RXRA (0.48) | RXRARARBRARGRARARXRB | |
| SCHEMBL8907180 | 0.82 | RXRA (0.42) | RXRARARBRARGRARARXRB | |
| SCHEMBL8905104 | 0.81 | RXRA (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL8905864 | 0.81 | RXRA (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL8905589 | 0.80 | THRA (0.34) | RXRA | |
| SCHEMBL8905583 | 0.80 | THRA (0.34) | RXRA | |
| SCHEMBL8905251 | 0.79 | RXRA (0.53) | RXRARARBRARGRARARXRB | |
| SCHEMBL10843886 | 0.79 | RARA (0.50) | RXRARARBRARGRARARXRB | |
| SCHEMBL10843882 | 0.79 | RARA (0.50) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | claimed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |