Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARG | P13631 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | HNF4A | P41235 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905256 | 0.97 | RXRA (0.47) | RXRARARARARBRARGRXRB | |
| SCHEMBL8904420 | 0.84 | RXRA (0.48) | RXRARARARARBRARGRXRB | |
| SCHEMBL8907180 | 0.84 | RXRA (0.42) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905583 | 0.83 | THRA (0.34) | RXRAPPARG | |
| SCHEMBL8905589 | 0.83 | THRA (0.34) | RXRAPPARG | |
| SCHEMBL8905104 | 0.80 | RXRA (0.49) | RXRARARARARBRARGRXRB | |
| SCHEMBL8905864 | 0.80 | RXRA (0.49) | RXRARARARARBRARGRXRB | |
| SCHEMBL8906010 | 0.80 | RXRA (0.49) | RXRARARARARBRARGRXRB | |
| SCHEMBL10844151 | 0.78 | RARA (0.48) | RXRARARARARBRARGRXRB | |
| SCHEMBL10841056 | 0.78 | RARA (0.48) | RXRARARARARBRARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | claimed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |