Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905157 | 0.94 | ALDH1A1 (0.33) | RORCALDH1A1TP53SMN1; SMN2LMNA | |
| SCHEMBL8907232 | 0.82 | CYP3A4 (0.31) | RORCALDH1A1THRBHPGD | |
| SCHEMBL8905446 | 0.82 | AGTR1 (0.38) | — | |
| SCHEMBL8905887 | 0.77 | EDNRA (0.37) | PPARGEDNRA | |
| SCHEMBL8788895 | 0.76 | PPARG (0.64) | PPARG | |
| SCHEMBL8906329 | 0.76 | CYP1A2 (0.33) | — | |
| SCHEMBL8907135 | 0.73 | AGTR1 (0.36) | EDNRA | |
| SCHEMBL8905483 | 0.72 | AGTR1 (0.38) | — | |
| SCHEMBL8788798 | 0.71 | PPARG (0.54) | PPARGRORCEDNRA | |
| SCHEMBL8906550 | 0.71 | ALDH1A1 (0.41) | PPARGALDH1A1TP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |