Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906593 | 0.95 | GPR119 (0.41) | GPR119MAPTMEN1HTTKMT2A | |
| SCHEMBL8905734 | 0.93 | GPR119 (0.42) | GPR119MAPTMEN1HTTKMT2A | |
| SCHEMBL8905548 | 0.84 | GPR119 (0.37) | GPR119MAPTMEN1HTTKMT2A | |
| SCHEMBL8907335 | 0.82 | PPARG (0.39) | AGTR1AGTR2NPSR1PDE3AKDM4E | |
| SCHEMBL8906713 | 0.81 | AGTR1 (0.45) | AGTR1AGTR2NPSR1PDE3AKDM4E | |
| SCHEMBL8906575 | 0.81 | AGTR2 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8906985 | 0.80 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8905963 | 0.79 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8906651 | 0.79 | GPR119 (0.38) | GPR119MAPTMEN1HTTKMT2A | |
| SCHEMBL8905662 | 0.79 | AGTR1 (0.39) | AGTR1AGTR2MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |