Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906188 | 0.90 | PDE4A (0.33) | PDE4BPDE4APDE4CPDE4DPPARG | |
| SCHEMBL8906651 | 0.85 | GPR119 (0.38) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL8905626 | 0.84 | PDE4A (0.43) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL8788746 | 0.82 | PPARG (0.48) | PPARG | |
| SCHEMBL8905548 | 0.81 | GPR119 (0.37) | PDE3APDE3B | |
| SCHEMBL8906629 | 0.80 | GPR119 (0.39) | PDE4BPDE3APDE4APDE4CPDE4D | |
| SCHEMBL8905804 | 0.80 | KDM4E (0.40) | PDE3APDE4APDE4DPPARG | |
| SCHEMBL8906566 | 0.79 | TAS2R8 (0.33) | PPARG | |
| SCHEMBL8905647 | 0.79 | CYP1A2 (0.33) | PPARG | |
| SCHEMBL8907533 | 0.77 | CYP3A4 (0.34) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |