Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905647 | 0.95 | CYP1A2 (0.33) | HPGD | |
| SCHEMBL8905546 | 0.93 | CYP3A4 (0.34) | AGTR1AGTR2 | |
| SCHEMBL8907613 | 0.89 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL8905653 | 0.88 | CYP3A4 (0.35) | AGTR1AGTR2 | |
| SCHEMBL8907533 | 0.88 | CYP3A4 (0.34) | AGTR1 | |
| SCHEMBL8905761 | 0.87 | AGTR1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL8907815 | 0.84 | CYP1A2 (0.32) | — | |
| SCHEMBL8906938 | 0.84 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL8905804 | 0.84 | KDM4E (0.40) | AGTR1AGTR2HPGD | |
| SCHEMBL8905936 | 0.84 | GPR119 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |