SCHEMBL8905936

SCHEMBL8905936

CCCCc1nc2ccc(-c3ccc(=O)[nH]n3)cc2n1-c1ccc(-c2ccccc2)c(-c2nnn[nH]2)c1C

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8906411 0.93 GPR119 (0.38) GPR119
SCHEMBL8907613 0.85 AGTR1 (0.37)
SCHEMBL8906342 0.84 GPR119 (0.37) GPR119
SCHEMBL8906575 0.84 AGTR2 (0.41)
SCHEMBL8905755 0.84 AGTR1 (0.33)
SCHEMBL8905548 0.83 GPR119 (0.37) GPR119MAPT
SCHEMBL8905546 0.82 CYP3A4 (0.34)
SCHEMBL8905230 0.82 KDM4E (0.35) GPR119MAPT
SCHEMBL8906938 0.82 AGTR1 (0.32)
SCHEMBL8906546 0.81 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684029-A HYPOTENSIVE AGENTS KARL THOMAE GMBH (DE) 1997-11-04 US disclosed