Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 6/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910883 | 0.91 | GAA (0.36) | GAAFDPSPTPN1FBP1CYP2C9 | |
| SCHEMBL459068 | 0.75 | FDPS (0.39) | GAAFDPSCYP2C9CYP2C19P2RX7 | |
| SCHEMBL7443950 | 0.75 | TSHR (0.35) | ALDH1A1POLBHTTGRM5 | |
| SCHEMBL7241548 | 0.73 | ALDH1A1 (0.39) | GAAFDPSCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL939997 | 0.72 | PGK1 (0.46) | FDPSP2RX7 | |
| SCHEMBL3359610 | 0.69 | TSHR (0.59) | GAAFBP1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL459237 | 0.69 | TSHR (0.40) | FDPS | |
| Phosphoric Acid SCHEMBL459067 | 0.67 | FDPS (0.38) | GAAFDPSALDH1A1P2RX7 | |
| Phosphoric Acid SCHEMBL938025 | 0.67 | FDPS (0.38) | GAAFDPSALDH1A1P2RX7 | |
| SCHEMBL13262247 | 0.67 | ALDH1A1 (0.33) | ALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693798-A | ACTIVE AGAINST RETROVIRAL DISEASES; PROPHYLAXIS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-12-02 | — | — | US | claimed |