Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.38 |
| ▸ | MVD | P53602 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459068 | 0.84 | FDPS (0.39) | TSHRFDPS | |
| SCHEMBL2695544 | 0.77 | MVD (0.31) | BTN3A1MVDP2RY2 | |
| Pyrophosphoric Acid SCHEMBL459236 | 0.75 | FDPS (0.42) | BTN3A1FDPS | |
| SCHEMBL31429819 | 0.73 | FDPS (0.37) | FDPS | |
| (Pyridin-4-Yl)-Methyl-Diphosphate SCHEMBL1652034 | 0.73 | TSHR (0.52) | TSHRBTN3A1FDPSFNTAFNTB | |
| SCHEMBL1110552 | 0.72 | TSHR (0.78) | TSHRBTN3A1FNTAFNTB | |
| SCHEMBL22235085 | 0.71 | FDPS (0.50) | TSHRBTN3A1FDPS | |
| SCHEMBL8905757 | 0.69 | GAA (0.39) | FDPS | |
| SCHEMBL17981684 | 0.68 | FDPS (0.33) | P2RY2FDPS | |
| Pyrophosphoric Acid SCHEMBL28298467 | 0.66 | HSP90AA1 (0.55) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022411-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | BIOSYNTIA APS (DK) | 2026-01-22 | — | — | US | disclosed |
| EP-4555076-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | Biosyntia ApS (DK) | 2025-05-21 | — | — | EP | disclosed |
| US-20240368659-A1 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | BIOSYNTIA APS (DK) | 2024-11-07 | — | — | US | disclosed |
| EP-4370653-A2 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | Biosyntia ApS (DK) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024013212-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | BIOSYNTIA APS (DK) | 2024-01-18 | — | — | WO | disclosed |
| WO-2023285585-A2 | MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS | BIOSYNTIA APS (DK) | 2023-01-19 | — | — | WO | disclosed |
| US-9057063-B2 | Genetically modified biological cells | O'Keefe, Theresa (US) | 2015-06-16 | — | — | US | disclosed |
| US-20130198900-A1 | \"THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS\ | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2013-08-01 | — | — | US | disclosed |
| EP-2614150-A1 | THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS | Yeda Research and Development Co. Ltd. (IL) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032522-A1 | THIAMINE PYROPHOSPHATE (TPP) RIBOSWITCH MUTANTS PRODUCING VITAMIN B1 ENRICHED FOOD AND FEED CROPS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2012-03-15 | — | — | WO | disclosed |
| US-7869957-B2 | Methods and systems to identify operational reaction pathways | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-11 | — | — | US | disclosed |
| US-20100304432-A1 | GENETICALLY MODIFIED BIOLOGICAL CELLS | O'KEEFE, THERESA | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022411-A1 | MICROBIAL CELL FACTORIES PRODUCING THIAMINE | AHCY, SHMT1, MTHFD1 | TSHR 1996/4885BTN3A1 3190/4885MVD 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.