Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15993770 | 0.66 | NOTUM (0.33) | — | |
| SCHEMBL8905911 | 0.65 | KMT2A (0.47) | KMT2A | |
| SCHEMBL29177032 | 0.62 | MMP2 (0.32) | — | |
| SCHEMBL2770223 | 0.62 | PEPD (0.43) | — | |
| SCHEMBL542421 | 0.61 | MMP2 (0.42) | — | |
| SCHEMBL18016774 | 0.61 | MMP2 (0.42) | — | |
| SCHEMBL542420 | 0.61 | MMP2 (0.42) | — | |
| SCHEMBL16611181 | 0.61 | ALDH1A1 (0.43) | — | |
| SCHEMBL16611180 | 0.61 | ALDH1A1 (0.43) | — | |
| SCHEMBL27799008 | 0.60 | CHRM2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616586-A | Tricyclic quinoxalinediones | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0642508-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993008188-A1 | TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-04-29 | — | — | WO | disclosed |