Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21193581 | 0.85 | RAB9A (0.51) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL8773482 | 0.83 | MEN1 (0.69) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL8904883 | 0.83 | MEN1 (0.69) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL26939090 | 0.81 | MEN1 (0.67) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL17885994 | 0.81 | MEN1 (0.67) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12536455 | 0.80 | MEN1 (0.65) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL20424232 | 0.80 | NPC1 (0.49) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL30453104 | 0.79 | KMT2A (0.44) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL29213509 | 0.78 | RIPK1 (0.50) | MEN1KMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7113805 | 0.77 | LMNA (0.70) | MEN1KMT2AHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425666-A | Preparation method of spirolactam cyclohexadiene compound | 华南理工大学 | 2023-07-14 | — | — | CN | disclosed |
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |