Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907287 | 0.94 | AGTR1 (0.36) | AGTR1AGTR2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8905230 | 0.82 | KDM4E (0.35) | AGTR1AGTR2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8906550 | 0.77 | ALDH1A1 (0.41) | AGTR1AGTR2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8907575 | 0.76 | LMNA (0.35) | AGTR1AGTR2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9095319 | 0.75 | PPARG (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL8905237 | 0.75 | KDM4E (0.36) | AGTR1AGTR2HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9095098 | 0.70 | PPARG (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL8906831 | 0.70 | ALDH1A1 (0.44) | HPGDRAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL8906713 | 0.70 | AGTR1 (0.45) | AGTR1AGTR2NPSR1KDM4EALDH1A1 | |
| SCHEMBL9259419 | 0.70 | AGTR1 (0.47) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |