Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906176 | 0.94 | AGTR1 (0.38) | AGTR1AGTR2TSHRTP53ALDH1A1 | |
| SCHEMBL8905230 | 0.76 | KDM4E (0.35) | AGTR1AGTR2TSHRTP53ALDH1A1 | |
| SCHEMBL9095098 | 0.75 | PPARG (0.64) | AGTR1AGTR2 | |
| SCHEMBL8907575 | 0.71 | LMNA (0.35) | AGTR1AGTR2ALDH1A1MAPTHPGD | |
| SCHEMBL9095319 | 0.70 | PPARG (0.64) | AGTR1AGTR2 | |
| SCHEMBL8906550 | 0.70 | ALDH1A1 (0.41) | AGTR1AGTR2TSHRTP53ALDH1A1 | |
| SCHEMBL8905237 | 0.69 | KDM4E (0.36) | AGTR1AGTR2TSHRTP53ALDH1A1 | |
| SCHEMBL2687005 | 0.67 | KDM4E (0.47) | TSHRTP53ALDH1A1MAPTHPGD | |
| SCHEMBL28265565 | 0.67 | KDM4E (0.54) | TSHRTP53P2RY14ALDH1A1MAPT | |
| SCHEMBL22746649 | 0.67 | NPC1 (0.37) | TSHRTP53HPSEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684029-A | HYPOTENSIVE AGENTS | KARL THOMAE GMBH (DE) | 1997-11-04 | — | — | US | disclosed |