Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651828 | 0.80 | HTR7 (0.69) | HTR7CHRM4GRIN2BDRD2CTSK | |
| Hydrochloric Acid SCHEMBL9393283 | 0.79 | HTR7 (0.68) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL8906894 | 0.77 | HTR7 (0.61) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL8907199 | 0.76 | HTR7 (0.63) | HTR7CHRM4GRIN2BDRD2CTSK | |
| Fenharmane SCHEMBL9695673 | 0.75 | GRIN2B (1.00) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL8906099 | 0.75 | HTR7 (0.64) | HTR7CHRM4GRIN2BDRD2CTSK | |
| Fenharmane SCHEMBL9696484 | 0.74 | GRIN2B (0.97) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL8322968 | 0.72 | GRIN2B (0.70) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL21883968 | 0.72 | GRIN2B (0.70) | HTR7CHRM4GRIN2BDRD2CTSK | |
| SCHEMBL10924004 | 0.72 | GRIN2B (0.70) | HTR7CHRM4GRIN2BDRD2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000871-A1 | TETRAHYDRO-BETACARBOLINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | claimed |
| WO-1997000871-A1 | TETRAHYDRO-BETACARBOLINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |