Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020282 | 0.83 | HSD17B3 (0.67) | SMN1; SMN2MAPTHTTALDH1A1MEN1 | |
| SCHEMBL339492 | 0.82 | ALOX15 (0.81) | ALOX15SMN1; SMN2MAPTPPARDALDH1A1 | |
| SCHEMBL25211873 | 0.80 | MAOB (0.77) | SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL25190661 | 0.80 | MAOB (0.77) | SMN1; SMN2MAPTMEN1KMT2A | |
| Lithium Ion SCHEMBL8907286 | 0.80 | MAPT (0.54) | SMN1; SMN2MAPTHTTALDH1A1TSHR | |
| SCHEMBL7996336 | 0.77 | LMNA (0.63) | ALOX15HTTALDH1A1FFAR1MEN1 | |
| SCHEMBL29955055 | 0.77 | LMNA (0.63) | ALOX15HTTALDH1A1FFAR1MEN1 | |
| SCHEMBL7307650 | 0.77 | GAA (0.62) | SMN1; SMN2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL503652 | 0.76 | L3MBTL1 (0.66) | ALOX15SMN1; SMN2MAPTALDH1A1FFAR1 | |
| SCHEMBL656832 | 0.76 | LMNA (0.67) | ALOX15SMN1; SMN2MAPTPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |