SCHEMBL8907297

SCHEMBL8907297

Cc1ccc(CC(=O)NC2(C(=O)O)CCCCC2C)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
P2RX7 Q99572 3/20 0.38
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.35
PSMB8 P28062 1/20 0.35
PSMB5 P28074 1/20 0.35
CCR2 P41597 2/20 0.35
GRIN2B Q13224 1/20 0.34
FPR3 P25089 1/20 0.34
FPR2 P25090 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657819 0.90 P2RX7 (0.42) P2RX7LMNAHPGDKMT2A
SCHEMBL8906967 0.89 L3MBTL1 (0.40) POLBL3MBTL1NPC1RAB9AP2RX7
SCHEMBL8650736 0.89 NPC1 (0.38) POLBL3MBTL1NPC1RAB9AP2RX7
SCHEMBL7960270 0.87 ALDH1A1 (0.48) POLBNPC1RAB9AHPGDKMT2A
SCHEMBL8905461 0.85 GAA (0.36) POLBP2RX7LMNAHPGDKMT2A
SCHEMBL8907562 0.81 SIGMAR1 (0.44) P2RX7KMT2A
SCHEMBL8655033 0.81 SMN1; SMN2 (0.40) P2RX7LMNAHPGDKMT2A
SCHEMBL7960620 0.78 NPC1 (0.36) L3MBTL1NPC1RAB9ALMNAHPGD
SCHEMBL7959997 0.78 ALDH1A1 (0.48) POLBNPC1RAB9AHPGDKMT2A
SCHEMBL8652620 0.78 NPC1 (0.37) POLBL3MBTL1NPC1RAB9AP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677449-A PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5462913-A Pesticides, insecticides, miticides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed