Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330833 | 0.95 | TSHR (0.34) | TSHRLMNAHSD17B10TDP1 | |
| SCHEMBL2172101 | 0.85 | LMNA (0.38) | LMNAFOLH1ENPEPANPEPGSTK1 | |
| SCHEMBL332035 | 0.84 | LMNA (0.33) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL21835883 | 0.81 | LMNA (0.36) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL331859 | 0.77 | LMNA (0.33) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL28597998 | 0.77 | MAPT (0.35) | TSHRLMNAKMT2ATDP1 | |
| SCHEMBL23152032 | 0.76 | NR1I2 (0.32) | LMNAHSD17B10TDP1 | |
| SCHEMBL7528601 | 0.74 | APEX1 (0.37) | TSHRLMNATDP1FOLH1ENPEP | |
| SCHEMBL27897055 | 0.74 | ALDH1A1 (0.43) | TSHRLMNAKMT2ATDP1 | |
| SCHEMBL5068252 | 0.73 | HSD17B10 (0.39) | TSHRLMNAHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110799573-B | Photochromic polyrotaxane compound, and curable composition comprising same | 株式会社德山 | 2022-06-03 | — | — | CN | disclosed |
| CN-112424260-A | Photochromic compound and curable composition containing same | 株式会社德山 | 2021-02-26 | — | — | CN | disclosed |
| CN-110869355-A | Benzopyran compound, curable composition containing benzopyran compound, and optical article containing cured product formed from curable composition | 株式会社德山 | 2020-03-06 | — | — | CN | disclosed |
| CN-110799573-A | Photochromic polyrotaxane compound, and curable composition comprising same | 株式会社德山 | 2020-02-14 | — | — | CN | disclosed |
| EP-2253626-B1 | THIETANE COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, RESIN, METHOD FOR PRODUCING THE RESIN, AND USE OF THE POLYMERIZABLE COMPOSITION AND THE RESIN | MITSUI CHEMICALS INC (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-8362280-B2 | Thietane compound, polymerizable composition containing the same, resin, method for producing the resin, and use of the polymerizable composition and the resin | MITSUI CHEMICALS, INC. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20120082793-A1 | DISPERSOID HAVING METAL-OXYGEN BONDS, METAL OXIDE FILM, AND MONOMOLECULAR FILM | NIPPON SODA CO., LTD. (JP) | 2012-04-05 | — | — | US | disclosed |
| EP-1422197-B1 | DISPERSED INGREDIENT HAVING HAVING METAL- OXYGEN | NIPPON SODA CO (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-20110135878-A1 | Dispersoid having metal-oxygen bonds, metal oxide film, and monomolecular film | NIPPON SODA, CO., LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
| US-20110136977-A1 | METAL COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, RESIN, METHOD FOR PRODUCING THE RESIN, AND USE OF THE RESIN | MITSUI CHEMICALS, INC. (JP) | 2011-06-09 | — | — | US | disclosed |
| EP-1134242-A2 | Plastic lenses for spectacles | HOYA CORPORATION (JP) | 2001-09-19 | — | — | EP | disclosed |
| EP-1085349-A2 | Plastic lenses having good ultraviolet absorbability, and method for the production thereof | HOYA CORPORATION (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0676429-B1 | Composition for urethane-based plastic lens | MITSUI CHEMICALS INC (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0630927-B1 | Optical urethane resin | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5576412-A | POLYURETHANES FORMED BY REACTION OF ALCOHOL OR MERCAPTAN WITH ISO(THIO)CYANATE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0506315-B1 | Optical urethane resins and plastic lenses comprising the same | MITSUI TOATSU CHEMICALS (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0676429-A2 | Composition for urethane-base plastic lens | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0630927-A2 | Optical urethane resin | Takeda Chemical Industries, Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5194559-A | Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0506315-A2 | Optical urethane resins and plastic lenses comprising the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136977-A1 | METAL COMPOUND, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, RESIN, METHOD FOR PRODUCING THE RESIN, AND USE OF THE RESIN | TERB1, TPR, POT1 | TSHR 1025/4885LMNA 3761/4885KMT2A 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.