Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 11/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8907581 | 0.99 | POLB (0.44) | SLC2A1TOP2AFLT3POLBTP53 | |
| SCHEMBL8906085 | 0.73 | SLC2A1 (0.71) | SLC2A1TOP2AFLT3POLBALDH1A1 | |
| SCHEMBL8907203 | 0.73 | FLT3 (0.50) | SLC2A1TOP2AFLT3POLBKDM4E | |
| Hydrochloric Acid SCHEMBL8891454 | 0.72 | POLB (0.72) | SLC2A1TOP2AFLT3POLBALDH1A1 | |
| SCHEMBL4874795 | 0.68 | KMT2A (0.57) | SLC2A1TOP2ALMNAMAPTGAA | |
| SCHEMBL21230580 | 0.68 | ELANE (0.54) | SLC2A1POLBTP53KDM4EALDH1A1 | |
| SCHEMBL18124747 | 0.66 | SLC29A1 (0.42) | KDM4E | |
| SCHEMBL4172267 | 0.66 | PARP1 (0.44) | POLBLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL8907169 | 0.65 | APP (0.62) | SLC2A1TOP2AFLT3POLBGAA | |
| SCHEMBL8908237 | 0.65 | KDM4E (0.46) | SLC2A1TOP2AFLT3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |