Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794913 | 0.87 | ALDH1A1 (0.31) | CA1CA2 | |
| SCHEMBL18435221 | 0.84 | MMP1 (0.33) | MMP9MMP1MMP2MMP3MMP8 | |
| SCHEMBL15840402 | 0.83 | METAP1 (0.35) | MMP9MMP1MMP2MMP3MMP8 | |
| SCHEMBL7061219 | 0.77 | PSMB5 (0.50) | CNR2CNR1MMP9MMP1MMP2 | |
| SCHEMBL20056731 | 0.75 | CYP3A4 (0.43) | MMP9MMP1MMP2MMP3MMP8 | |
| SCHEMBL13402971 | 0.75 | ACACB (0.33) | CA1CA2 | |
| SCHEMBL15705287 | 0.74 | ADAM17 (0.37) | CNR2MMP1MMP2MMP8ADAM17 | |
| SCHEMBL24995704 | 0.74 | CNR2 (0.36) | CNR2CNR1MMP9FCER2ADAM17 | |
| SCHEMBL21543027 | 0.74 | CNR2 (0.36) | CNR2CNR1MMP9FCER2PDF | |
| SCHEMBL2784044 | 0.74 | CNR2 (0.36) | CNR2CNR1MMP9FCER2PDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813543-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028464-A1 | BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-19 | — | — | WO | disclosed |