Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 16/20 | 0.35 |
| ▸ | MMP3 | P08254 | 14/20 | 0.35 |
| ▸ | MMP2 | P08253 | 12/20 | 0.35 |
| ▸ | MMP9 | P14780 | 8/20 | 0.35 |
| ▸ | MMP8 | P22894 | 5/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP7 | P09237 | 6/20 | 0.33 |
| ▸ | MMP20 | O60882 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
| ▸ | MMP16 | P51512 | 1/20 | 0.32 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.32 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907474 | 0.83 | CNR2 (0.36) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL1219005 | 0.81 | METAP1 (0.38) | METAP1CTSKMMP1MMP3MMP2 | |
| SCHEMBL15840471 | 0.79 | KMT2A (0.37) | CTSK | |
| SCHEMBL15705303 | 0.77 | CTSK (0.34) | CTSKMMP1MMP3MMP2MMP9 | |
| SCHEMBL1215890 | 0.76 | MAOA (0.47) | METAP1CTSK | |
| SCHEMBL18435221 | 0.75 | MMP1 (0.33) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL15840455 | 0.75 | NMT1 (0.36) | METAP1 | |
| SCHEMBL15839931 | 0.74 | KEAP1 (0.33) | METAP1 | |
| SCHEMBL17323496 | 0.74 | KEAP1 (0.33) | METAP1 | |
| SCHEMBL15840416 | 0.73 | BMP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014095773-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-26 | — | — | WO | disclosed |