Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TOP1 | P11387 | 4/20 | 0.50 |
| ▸ | CYCS | P99999 | 4/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865497 | 0.85 | MAPT (0.41) | MAPTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL8907605 | 0.84 | ABCG2 (0.52) | MAPTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL29558419 | 0.82 | TOP1 (0.61) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3794157 | 0.82 | TOP1 (0.61) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29454950 | 0.79 | TERT (0.55) | MAPTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL8865224 | 0.79 | MAPT (0.41) | MAPTTOP1CYCSABCG2 | |
| Hydrochloric Acid SCHEMBL8865004 | 0.79 | TOP1 (0.53) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL10730297 | 0.79 | MEN1 (0.57) | TOP1CYCSABCG2ENPP2 | |
| SCHEMBL8865525 | 0.75 | TOP1 (0.58) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL10726864 | 0.74 | ENPP2 (0.69) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| US-5674467-A | USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY | INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) | 1997-10-07 | — | — | US | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |