Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | CYCS | P99999 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865844 | 0.86 | ADORA2A (0.37) | ABCG2TOP1CYCSADORA2AADORA2B | |
| SCHEMBL8907605 | 0.85 | ABCG2 (0.52) | ABCG2TOP1CYCSADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL8865180 | 0.81 | TOP1 (0.47) | ABCG2TOP1CYCSTERTENPP2 | |
| SCHEMBL9615191 | 0.76 | TERT (0.46) | ABCG2TOP1CYCSTERTENPP2 | |
| SCHEMBL14629716 | 0.75 | F9 (0.43) | ABCG2TOP1CYCSADORA2AADORA2B | |
| SCHEMBL8865842 | 0.74 | PDE3B (0.48) | ABCG2TOP1CYCSPDE3BPDE3A | |
| SCHEMBL12843222 | 0.73 | CYCS (0.63) | ABCG2TOP1CYCSTERTALDH1A1 | |
| SCHEMBL30616085 | 0.72 | ABCG2 (0.49) | ABCG2TOP1CYCSTERTALDH1A1 | |
| SCHEMBL29441514 | 0.72 | ABCG2 (0.49) | ABCG2TOP1CYCSTERTALDH1A1 | |
| SCHEMBL499168 | 0.72 | ABCG2 (0.49) | ABCG2TOP1CYCSTERTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684948-B1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | DIAGNOSTIKFORSCHUNG INST (DE) | 1997-10-22 | — | — | EP | disclosed |
| WO-1994019352-A1 | MESO-TETRAPHENYL PORPHYRIN COMPLEX COMPOUNDS, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1994-09-01 | — | — | WO | disclosed |