Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849066 | 0.84 | NPC1 (0.42) | NPC1RAB9AGFERNOTUMDHFR | |
| SCHEMBL28827806 | 0.81 | RAB9A (0.50) | NPC1RAB9ANOTUMDHFRADORA3 | |
| SCHEMBL6765172 | 0.80 | LMNA (0.47) | NPC1RAB9ADPP4ADORA3MEN1 | |
| SCHEMBL9869365 | 0.78 | NPC1 (0.68) | NPC1RAB9ANOTUMDHFRDPP4 | |
| SCHEMBL28827816 | 0.78 | NPC1 (0.47) | NPC1RAB9ANOTUMADORA3MEN1 | |
| SCHEMBL1976140 | 0.76 | CLK4 (0.48) | NPC1RAB9ADPP4ADORA3NR1H4 | |
| SCHEMBL17269507 | 0.76 | NPC1 (0.65) | NPC1RAB9ANOTUMDHFRDPP4 | |
| SCHEMBL14374410 | 0.76 | NPC1 (0.65) | NPC1RAB9ANOTUMDHFRDPP4 | |
| SCHEMBL28827831 | 0.75 | CTRC (0.47) | NPC1RAB9AADORA3SMN1; SMN2 | |
| SCHEMBL3166068 | 0.75 | NPC1 (0.58) | NPC1RAB9ANOTUMDHFRRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633112-A | Photosensitive resin composition containing a carboxylic acid polymer, photoacid generator and secondary or tertiary aliphatic amine | HITACHI, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |