Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecane SCHEMBL6896604 | 0.97 | GPR84 (0.62) | TP53GPR84FFAR1ACE2PPARD | |
| Hexadecane SCHEMBL29288627 | 0.97 | GPR84 (0.62) | TP53GPR84FFAR1ACE2PPARD | |
| Tetradecane SCHEMBL28188856 | 0.97 | GPR84 (0.62) | TP53GPR84FFAR1ACE2PPARD | |
| Lactic Acid SCHEMBL29116772 | 0.88 | LMNA (0.59) | TP53GPR84FFAR1ACE2PPARD | |
| Cetyl Alcohol SCHEMBL27360822 | 0.88 | LMNA (0.59) | TP53GPR84FFAR1ACE2PPARD | |
| Cetostearyl Alcohol SCHEMBL28027646 | 0.88 | LMNA (0.59) | TP53GPR84FFAR1ACE2PPARD | |
| Lactic Acid SCHEMBL10794173 | 0.88 | GPR84 (0.59) | TP53GPR84FFAR1ACE2PPARD | |
| Tetrabuthylammonium SCHEMBL331982 | 0.88 | SLC22A1 (0.55) | TP53GPR84FFAR1ACE2MAPT | |
| Lactic Acid SCHEMBL28942349 | 0.88 | TSHR (0.52) | TP53GPR84FFAR1ACE2PPARD | |
| Lactic Acid SCHEMBL27658059 | 0.88 | TSHR (0.52) | TP53GPR84FFAR1ACE2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880872-B | Preparation method and application of lactic acid rare earth complex and rare earth catalyst | 中国科学院长春应用化学研究所 | 2017-01-11 | — | — | CN | claimed |
| US-5603926-A | CONTAINS A (METH)ACRYLIC MONOMER HAVING AN AMINO GROUP | OSAKA YUKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-02-18 | — | — | US | disclosed |