Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 6/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958045 | 0.90 | LPAR1 (0.42) | LPAR1GAA | |
| SCHEMBL7964124 | 0.89 | LPAR1 (0.40) | LPAR1CYP1A2GAAEPHX2SHMT1 | |
| SCHEMBL8907276 | 0.88 | MAPT (0.34) | LPAR1CYP1A2GAANPSR1EPHX2 | |
| SCHEMBL8906307 | 0.85 | LPAR1 (0.39) | LPAR1CYP1A2PYGLSHMT1SHMT2 | |
| SCHEMBL8907090 | 0.85 | GPR132 (0.37) | LPAR1GAANPSR1EPHX2PYGL | |
| SCHEMBL8905958 | 0.84 | LPAR1 (0.35) | LPAR1GAANPSR1EPHX2PYGL | |
| SCHEMBL7957870 | 0.82 | LPAR1 (0.35) | LPAR1GAA | |
| SCHEMBL8906721 | 0.80 | KMT2A (0.48) | LPAR1GAASHMT1SHMT2P2RX7 | |
| SCHEMBL7960135 | 0.80 | HPGD (0.34) | LPAR1CYP1A2GAAEPHX2P2RX7 | |
| SCHEMBL8653800 | 0.80 | SHMT1 (0.43) | LPAR1SHMT1SHMT2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |