Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 6/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959967 | 0.90 | LPAR1 (0.39) | LPAR1GAA | |
| SCHEMBL7964477 | 0.89 | LPAR1 (0.37) | LPAR1P2RX7EPHX2 | |
| SCHEMBL8906207 | 0.88 | P2RX7 (0.32) | LPAR1GAANPSR1P2RX7TAS1R3 | |
| SCHEMBL8907090 | 0.86 | GPR132 (0.37) | LPAR1GAANPSR1P2RX7TAS1R3 | |
| SCHEMBL8907075 | 0.85 | NPC1 (0.39) | LPAR1P2RX7 | |
| SCHEMBL8907769 | 0.84 | LPAR1 (0.38) | LPAR1GAANPSR1P2RX7TAS1R3 | |
| SCHEMBL8907152 | 0.81 | P2RX7 (0.36) | GAANPSR1P2RX7PYGLCYP2C9 | |
| SCHEMBL7960049 | 0.81 | LPAR1 (0.33) | LPAR1GAA | |
| SCHEMBL8906535 | 0.81 | PYGL (0.34) | GAANPSR1P2RX7PYGLEPHX2 | |
| SCHEMBL8907295 | 0.81 | S1PR5 (0.35) | P2RX7PYGLCYP2C9SHMT1SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677449-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5462913-A | Pesticides, insecticides, miticides, herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |