Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620797 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL5383978 | 0.78 | CA1 (0.39) | — | |
| SCHEMBL1620557 | 0.78 | CA1 (0.39) | — | |
| SCHEMBL1010833 | 0.74 | CA2 (0.41) | — | |
| SCHEMBL7342226 | 0.74 | PPARG (0.31) | — | |
| SCHEMBL28654089 | 0.72 | ALOX12 (0.37) | — | |
| SCHEMBL8405501 | 0.70 | — | — | |
| SCHEMBL8700619 | 0.70 | CA2 (0.33) | — | |
| SCHEMBL4580139 | 0.68 | — | — | |
| SCHEMBL8126043 | 0.68 | CA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686478-A | Endothelin antagonists | MERCK & CO. INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0710235-A4 | — | — | 1996-06-12 | — | — | EP | disclosed |
| EP-0710235-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO. INC. (US) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003295-A1 | ENDOTHELIN ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | disclosed |