Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 10/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909052 | 0.79 | CYP3A4 (0.55) | RARGRARARARBPPARGCYP3A4 | |
| SCHEMBL8907954 | 0.74 | RARG (0.44) | RARGRARARARBPPARGL3MBTL1 | |
| SCHEMBL9270229 | 0.71 | RARG (0.62) | RARGRARARARBPPARGCYP3A4 | |
| SCHEMBL8907772 | 0.70 | PARP15 (0.50) | PPARGKDM4ENPC1GAARAB9A | |
| SCHEMBL9263958 | 0.68 | MAOB (0.51) | PPARGL3MBTL1CYP3A4CYP26A1CYP26B1 | |
| SCHEMBL8907967 | 0.66 | CYP26A1 (0.56) | RARGRARARARBPPARGCYP3A4 | |
| SCHEMBL9261830 | 0.66 | MAOB (0.46) | L3MBTL1CYP3A4KDM4ENPC1GAA | |
| SCHEMBL8907475 | 0.65 | CYP3A4 (0.52) | RARGRARARARBPPARGCYP3A4 | |
| SCHEMBL9271838 | 0.65 | CYP26A1 (0.64) | RARGRARARARBPPARGCYP3A4 | |
| SCHEMBL8839372 | 0.65 | TDP1 (0.46) | PPARGL3MBTL1CYP3A4RAB9ACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654331-A | SKIN AND RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1997-08-05 | — | — | US | disclosed |