Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523060 | 0.79 | SMN1; SMN2 (0.38) | CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29692994 | 0.79 | GABBR2 (0.43) | CA2CA12CA9ELANE | |
| SCHEMBL502464 | 0.79 | GABBR2 (0.43) | CA2CA12CA9ELANE | |
| SCHEMBL8908019 | 0.76 | CA1 (0.44) | CA2CA1EGFRGAAALDH1A1 | |
| SCHEMBL6976097 | 0.72 | MAPT (0.36) | CA2KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28506063 | 0.71 | CA2 (0.53) | CA2CA1EGFRGAAALDH1A1 | |
| SCHEMBL6830309 | 0.70 | AKR1B1 (0.41) | CA2KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL7158271 | 0.70 | CA1 (0.44) | CA2CA1EGFRGAAKDM4E | |
| SCHEMBL7089410 | 0.70 | GAA (0.39) | GAAKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8634112 | 0.69 | CA1 (0.37) | CA2CA1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872839-B1 | Benzofuran-2-one | CIBASPECIALTY CHEMICALS CORP. (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1159276-B1 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | CIBA SC HOLDING AG (CH) | 2003-10-22 | — | — | EP | disclosed |
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6533825-B2 | For colouring/pigmenting high-molecular-weight organic material | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-03-18 | — | — | US | disclosed |
| US-6503937-B1 | Coloring agents for high molecular weight materials such as polymers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-07 | — | — | US | disclosed |
| EP-1123289-B1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONES | CIBA SC HOLDING AG (CH) | 2002-11-27 | — | — | EP | disclosed |
| US-20020095046-A1 | Dibenzonaphthyrones | NESVADBA PETER (CH) | 2002-07-18 | — | — | US | disclosed |
| EP-1015518-B1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SC HOLDING AG (CH) | 2002-05-15 | — | — | EP | disclosed |
| EP-1159276-A2 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| US-6323267-B1 | MIXING HIGH MOLECULAR WEIGHT ORGANIC OR INORGANIC MATERIAL WITH ISOXINDIGO COMPOUND | CIBA SPECIALTY CHEMICALS CORP. | 2001-11-27 | — | — | US | disclosed |
| US-6281361-B1 | COLORING, PIGMENTING | CIBA SPECIALTY CHEMICALS CORP. | 2001-08-28 | — | — | US | disclosed |
| EP-1123289-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | Ciba SC Holding AG (CH) | 2001-08-16 | — | — | EP | disclosed |
| EP-1095041-A2 | DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL | Ciba SC Holding AG (CH) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000053597-A2 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-09-14 | — | — | WO | disclosed |
| EP-1015518-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | Ciba SC Holding AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000024736-A1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-04 | — | — | WO | disclosed |
| WO-1999052909-A2 | DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL | CIBA SPECIALTY CHEMICAL HOLDING INC. (CH) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999013007-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-03-18 | — | — | WO | disclosed |
| US-5187161-A | Antiinflammatory agents | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0414913-A1 | p-AMINOPHENOL DERIVATIVE AND PRODUCTION AND APPLICATION THEREOF | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | CYP1B1, CYP1A1, ECI1 | CA2 1668/4885CA1 1512/4885EGFR 4081/4885 |
| US-20020095046-A1 | Dibenzonaphthyrones | CYP1B1, CYP7B1, CYP1A1 | CA2 4156/4885CA1 3579/4885EGFR 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.