SCHEMBL8908242

SCHEMBL8908242

CCCC[Sn](CCCC)(CCCC)CCCC.c1ccc([Sn](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.35
PCSK9 Q8NBP7 1/20 0.35
PTGS2 P35354 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
DNM1 Q05193 1/20 0.32
TP53 P04637 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442385 0.77 SIGMAR1 (0.39) LTA4HPCSK9PTGS2MEN1KMT2A
SCHEMBL276811 0.77 LTA4H (0.38) LTA4HPCSK9PTGS2MEN1KMT2A
SCHEMBL1030650 0.77 LTA4H (0.38) LTA4HPCSK9PTGS2MEN1KMT2A
SCHEMBL8378237 0.77 SIGMAR1 (0.48) SMN1; SMN2SIGMAR1TP53
SCHEMBL28123637 0.77 KCNH2 (0.49) MEN1KMT2ASIGMAR1
SCHEMBL11680871 0.77 SIGMAR1 (0.48) SMN1; SMN2SIGMAR1TP53
Hydrogen Sulfide SCHEMBL9374535 0.76 DNM1 (0.37) LTA4HPCSK9PTGS2MEN1KMT2A
SCHEMBL1350580 0.74 DNM1 (0.44) MEN1KMT2ASMN1; SMN2SIGMAR1DNM1
SCHEMBL9745931 0.74 LTA4H (0.35) LTA4HPCSK9PTGS2MEN1KMT2A
SCHEMBL7083095 0.74 DNM1 (0.44) MEN1KMT2ASMN1; SMN2SIGMAR1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed