SCHEMBL8908300

SCHEMBL8908300

CC(C)(C)NS(=O)(=O)c1cccc(Cl)c1O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.49
ACLY P53396 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 2/20 0.41
HSD11B1 P28845 7/20 0.39
ALOX5AP P20292 2/20 0.38
FEN1 P39748 2/20 0.38
MAPK1 P28482 1/20 0.37
PARG Q86W56 1/20 0.37
PTGES2 Q9H7Z7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15560488 0.82 NSD2 (0.51) NSD2MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL3583413 0.82 NSD2 (0.50) NSD2MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL10386010 0.79 NSD2 (0.66) NSD2ACLYMEN1KMT2AMAPT
SCHEMBL12932761 0.78 LMNA (0.50) NSD2MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL2642805 0.76 HSD11B1 (0.42) ACLYMEN1KMT2AALDH1A1HSD11B1
SCHEMBL9540649 0.75 ACLY (0.43) ACLYMEN1KMT2AMAPTALDH1A1
SCHEMBL2803354 0.75 NSD2 (0.58) NSD2MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL1111419 0.74 NSD2 (0.50) NSD2ACLYMEN1KMT2AMAPT
SCHEMBL27812266 0.74 ACLY (0.42) ACLYMEN1KMT2AMAPTALDH1A1
SCHEMBL10423502 0.74 TTR (0.42) ACLYMEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5612173-A INDOPHENOL DYE EASTMAN KODAK COMPANY (US) 1997-03-18 US disclosed
EP-0574090-A1 One equivalent couplers and low pKa release dyes EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed