Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890119 | 0.78 | ALOX5 (0.57) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL1733690 | 0.76 | PARP10 (0.60) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL4013173 | 0.74 | PARP10 (0.62) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL9630177 | 0.73 | PARP10 (0.61) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8908585 | 0.73 | ALOX5 (0.46) | MAOBALOX5ALOX5AP | |
| SCHEMBL22874534 | 0.71 | PARP10 (0.66) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL6285192 | 0.71 | SMN1; SMN2 (0.54) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8471656 | 0.71 | PARP10 (0.58) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL510401 | 0.71 | PARP10 (0.51) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL5720536 | 0.71 | SMN1; SMN2 (0.54) | PARP10SMN1; SMN2ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012866-A1 | BIS-HETEROARYLYLMETHOXYPHENYLKETONE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-04-10 | — | — | WO | disclosed |